Battelle Memorial Institute

MANAGEMENT AND OPERATIONS OF THE INL

CHEMICAL, BIOLOGICAL, RADIOLOGICAL, AND NUCLEAR DEFENSE TESTING, ANALYTICS, AND SUSTAINMENT FOR CIISD

TO SUPPORT AND ASSIST THE NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES BY CONDUCTING ONGOING AND RECURRING EVALUATIONS OF THE TOXIC AND CARCINOGENIC POTENTIAL OF CHEMICAL, BIOLOGICAL AND PHYSICAL AGENTS THAT MAY POSE A HEALTH HAZARD TO HUMANS.

ARCTIC RESEARCH SUPPORT AND LOGISTICS SERVICES (ARSLS)

TASK ORDER UNDER THE DEVELOPMENT TEST & EVALUATION SUPPORT SERVICES BLANKET PURCHASE AGREEMENT TO BATTELLE MEMORIAL INSTITUTE FOR TIME AND MATERIALS FOR T&E PLANNING, EXECUTION, DATA COLLECTION, ANALYSIS & REPORTING.

VASCULAR ENGINEERED INTERNAL NETWORK THE OBJECTIVE OF THIS CONTRACT IS TO PROLONG THE SERVICEABILITY OF DOD STRUCTURES AND AIRFIELD PAVEMENTS BY DEVELOPING A REPARATIVE VASCULATURE FOR CONCRETE CONSISTING OF A FIBROUS VASCULAR STRUCTURE DECORATED WI

F999 - ADMINISTRATIVE AND PROGRAMMATIC SUPPORT SERVICES FOR THE ENDOCRINE DISRUPTOR SCREENING PROGRAM, OFFICE OF CHEMICAL SAFETY & POLLUTION PREVENTION (OCSPP).

FULL TIME EMPLOYEE & MAINTENANCE TASK ORDER

LARGE SUV COMMERCIAL MODIFICATION SERVICES - DEVELOPMENT OF ARMORED SUV PROTOTYPES FOR US GOVERNMENT USE

PEO-M TO 030 COMBATANT CRAFT MISSION EQUIPMENT (CCME) ACQUISITION SUPPORT

COP STUDIES SUPPORT VACCINE RD

LABOR, FACILITIES, MATERIALS AND SUPPLIES TO EXECUTE THE DARD MISSION

PALLETS FOR EMASS SYSTEM

TANKS AND TANK STANDS FOR EMASS

ARCTIC SCIENCE SUPPORT

SUPPORT INTEGRATION OF TOTAL LIFE CYCLE SYSTEMS MANAGEMENT OF CBD ASSETS

EVALUATION OF ERVEBO

MANUFACTURED PARTS FOR ARMORED VEHICLES

ULTRA-RARE GENE-BASED THERAPY NETWORK

ADVANCE THE COMPONENT-LEVEL EVALUATION OF THE HOOD/MASK INTERFACE THAT ACCURATELY PREDICTS THE PROTECTION PERFORMANCE IN THE NECK AND HEAD REGIONS WHEN THE PROTECTIVE GARMENT SYSTEM IS TESTED AT THE COMPONENT LEVEL (I.E., HMI) AND PREDICTION OF PERFORMANCE WHEN TESTED AS A FULL ENSEMBLE ON A HUMAN.

TOXICOLOGICAL EVALUATIONS FOR THE DIVISION OF TRANSLATIONAL

FABRICATION AND ASSEMBLY OF ACLES SHELTER IN ALASKA

TOXICOLOGICAL EVALUATIONS FOR THE DIVISION OF TRANSLATIONAL

PROTOTYPE DEVELOPMENT FOR MO3CHA TO5

SUPPORT TO ENABLE MICROSYSTEM CONTROL OF CATALYTIC FUNCTION

HILUX TRUCKS

SOLAR PHASE 2 SUPPORT

MBUF ADVISORY SUPPORT

RESEARCH AND DEVELOPMENT

FABRICATED ARMOR KITS FOR VEHICLES

SEPTEMBER COURSE RELEASES

FABRICATED PARTS FOR ARMORED VEHICLES

COMMUNICATION PARTS FOR VEHICLES

ARCTIC GATEWAY SERVICES APP25

SOLAR PHASE II SUPPORT

SOLAR PHASE 2 SUPPORT

***PURCHASE OF NHP'S****

DEVELOPMENT OF NON-PFAS MATERIAL

ANIMALS AND TESTING SERVICES.

WELD PARTS

A&E SERVICES

CONTRACT ANALYTICS SERVICES

RAT AND MOUSE SURROGATE S1500+ TEMPO-SEQ KIT

MAINTENANCE ON JSMLT MASK TESTERS

SUMMIT STATION TURNOVER FEB 25

PROVIDE PERSONNEL, MATERIALS, FACILITIES AND MANAGEMENT AS REQUIRED TO COMPLETE TASKS IN SUPPORT OF THE CONTRACT SOW.

DARPA PERSISTENT OCEANOGRAPHIC DEVICE POWER (PODPOWER)

PROVIDES ENGINEERING SERVICES IN SUPPORT OF THE TENSHU PROGRAM.

ENVIRONMENTAL CONSULTING SERVICES

2-312-0218781 MOD 9

TESTING LABORATORIES AND SERVICES

DIGITAL TWIN APPROACH IS BASED ON MERGING TWO EXISTING MODELING METHODS: FIRST-PRINCIPLES AND DATA-DRIVEN. MERGING TWO MODELING TECHNIQUES ALLOWS A MORE COMPLETE MODEL AS THE TWO APPROACHES COMPLEMENTS EACH OTHER COMBINING THEIR STRENGTHS AND ELIMINATING WEAKNESSES. THE FIRST-PRINCIPLES MODELING RELIES ON EITHER ORDINARY OR PARTIAL DIFFERENTIAL EQUATIONS DERIVED FROM KNOWN PHYSICS OR HUMAN PHYSIOLOGY LAWS AND PRINCIPLES. WHILE BEING A POWERFUL TOOL IN INVESTIGATING SYSTEM’S RESPONSE TO DIFFERENT INPUTS, THE FIRST-PRINCIPLES SYSTEMS DO NOT USE THE MOST CURRENT DATA AND CANNOT REFLECT THE IMMEDIATE CONDITIONS OF HUMAN PHYSIOLOGY. ALSO, THE FIRST-PRINCIPLES MODEL MAY NOT CONSIDER ALL FACTORS AFFECTING HUMAN’S RESPONSE TO STRESS AS SOME OF THEM ARE NOT KNOWN OR TWO COMPLEX TO DERIVE. ON THE OTHER HAND, THE ARTIFICIAL INTELLIGENCE/MACHINE LEARNING (AI/ML) -BASED DATA-DRIVEN MODELS CAN USE THE MOST RECENTLY COLLECTED DATA TO PRODUCE PARAMETERS PREDICTIONS AND CAN BE ADAPTED TO THE MOST IMMEDIATE DATA. HOWEVER, THESE DATA-DRIVEN ALGORITHMS TEND TO OVERFIT THE DATA AND MOST OF THEM LACK EXPLAINABILITY. DATA OVERFITTING LEADS TO MODELS WHICH PERFORM VERY WELL WITHING THE RANGE OF TRAINING DATA, HOWEVER, BREAKS DOWN ONCE THE NEW DATA ARE OUTSIDE OF THE HISTORICAL DATA. THE LACK OF EXPLAINABILITY UNDERMINES TRUST IN THESE MODELS AND LEADS TO RELUCTANCE IN ACCEPTING THEM FOR HUMAN-SAFETY RELATED APPLICATIONS. THE DIGITAL TWIN APPROACH ADDRESSES THE WEAKNESSES OF THESE TWO MODELING APPROACHES AND ALSO OFFERS AN OPPORTUNITY TO PROVIDE AN ANTICIPATORY PHYSIOLOGIC GUIDANCE TO THE MILITARY PERSONNEL BY FIRST APPLYING THE ANTICIPATED GUIDANCE TO THE TWIN MODEL PRIOR ADVISING IT TO THE PERSONNEL. THIS PROJECT WILL DEVELOP DIGITAL TWIN MODELS BASED ON PHYSICS-INFORMED DEEP NEURAL NETWORKS (PIDNNS). THE PHYSICS-INFORMED DEEP NEURAL NETWORKS (PIDNNS) WILL CONSIST OF THE FIRST-PRINCIPLE SCENARIO MODEL DEVELOPED AT USARIEM AND DATA-DRIVEN PART REPRESENTED BY A DEEP NEURAL NETWORK DEVELOPED BASED ON DATA COLLECTED FROM WEARABLE SENSOR SUITS. THE SCENARIO MODEL DEVELOPED AT USARIEM, WAS DESIGNED TO ESTIMATE AND PREDICT CORE TEMPERATURE, HEART RATE, AND SWEAT RATE, WITHOUT REQUIRING PRIOR KNOWLEDGE AND DIRECT MEASUREMENT OF THESE PHYSIOLOGICAL VARIABLES. THE UNDERLYING MODEL FOR SCENARIO SIMULATES THE TIME COURSE OF CORE TEMPERATURE VARIATIONS, WHILE TAKING INTO ACCOUNT DIFFERENT FACTORS THAT AFFECT HUMAN THERMOREGULATION. THE TEMPERATURE DISTRIBUTION WITHIN THE HUMAN BODY IS REPRESENTED BY A LUMP-PARAMETER MODEL CONSISTING OF SIX CONCENTRIC CYLINDRICAL COMPARTMENTS. HEAT FLOW IS THEN MODELED BY A SET OF MACROSCOPIC ENERGY CONSERVATION EQUATIONS BASED ON HEAT CONVECTION BETWEEN THE CENTRAL BLOOD COMPARTMENT AND THE ADJACENT CORE, MUSCLE, FAT, AND VASCULAR SKIN COMPARTMENTS; RADIAL HEAT CONDUCTION BETWEEN EVERY PAIR OF ADJACENT COMPARTMENTS; AND AIR CONVECTION, RADIATION, AND SWEAT EVAPORATION BETWEEN THE SUPERFICIAL AVASCULAR SKIN LAYER AND THE ENVIRONMENT AND TRANSITION THROUGH THE CLOTHING THE ENERGY CONSERVATION EQUATIONS ARE REPRESENTED BY A SET OF SIX ORDINARY DIFFERENTIAL EQUATIONS THAT CAN BE EXPRESSED AS A SYSTEM.