University Of Texas System

LARGE DIAMETER UUV SYSTEM CONFIGURATION

STX UROLOGY PHYSICIAN SERVICES

THIS IS FIRM-FIXED PRICE CONTRACT FOR CONSOLIDATED FACILITIES MANAGEMENT SERVICES (CFM) AT THE LYNDON B. JOHNSON PRESIDENTIAL LIBRARY AND MUSEUM FOR THE PERIOD OCTOBER 1, 2024 THROUGH SEPTEMBER 30, 2025 PLUS 4 OPTION YEARS.

OPERATION AND MAINTENANCE OF THE CHIMPANZEE CARE CENTER (CCC)

IGF::CL,CT::IGF THIS PROCUREMENT IS BEING PROCESSED AS A RESULT OF THE SCIENCE MISSION DIRECTORATE (SMD) LED COMPETITIVE ANNOUNCEMENT OF OPPORTUNITY #NNH12ZDA006O ENTITLED 'SECOND STAND ALONE MISSIONS OF OPPORTUNITY NOTICE (SALMON-2)' DATED FEBRUARY 7, 2012. THE REASON INSTRUMENT WAS SELECTED FOR AWARD AS DOCUMENTED VIA NASA HQ LETTER DATED AUGUST 6, 2015. THE GOAL OF THE EUROPA MISSION IS TO DELIVER A SCIENTIFICALLY RELEVANT MISSION THAT WILL INVESTIGATE EUROPA'S HABITABILITY BY ADDRESSING AT LEAST THE MAJORITY OF THE PLANETARY DECADAL SURVEY'S FIVE SCIENCE OBJECTIVES FOR EUROPA AS WELL AS INVESTIGATING POTENTIAL LANDING SITES FOR FUTURE EXPLORATION. IN ADDITION, THE MISSION WILL ATTEMPT TO IDENTIFY MATERIALS THAT ARE POTENTIALLY CONTAINED IN POSSIBLE WATER PLUMES. THE REASON INSTRUMENT INVESTIGATION WILL USE A DUAL FREQUENCY ICE PENETRATING RADAR TO PROBE THE SUBSURFACE OF EUROPA FROM THE ICY NEAR-SURFACE TO THE UNDERLYING OCEAN AND CHARACTERIZE THE SURFACE FOR FUTURE EXPLORATION. REASON IS UNIQUELY CAPABLE OF CHARACTERIZING THE STRUCTURE OF THE ICE SHELL, INCLUDING SUBSURFACE LIQUID WATER AND LAKES. THE STATEMENT OF WORK WILL INCLUDE REPORTING REQUIREMENTS, DELIVERABLES/OUTCOMES AND MILESTONES. SPECIFIC OBJECTIVES FOR THIS SCOPE OF WORK ARE FOR THE REASON INSTRUMENT PRINCIPAL INVESTIGATOR (PI) TO PROVIDE SUPPORT TO THE EUROPA PROJECT SCIENTIST IN THE PERFORMANCE OF HIS TASKS DURING THE DESIGN, DEVELOPMENT, FABRICATION, ASSEMBLY, INTEGRATION, TEST, AND LAUNCH PHASE OF THE EUROPA MISSION IMPLEMENTATION.

AGREEMENT: $6,746,364 AMD 1: $0 AMD 2: $0 AMD 3: $6,597,318 AMD 4: $8,331,980 AMD 5: $0 AMD 6: $1,000 TASK 5 WILL PROVIDE TARGETED AND NON-TARGETED METABOLITE PROFILING FOR PLASMA OR SERUM SAMPLES FROM INDIVIDUALS INCLUDED IN DESIGNATED NHLBI TRANS-OMICS FOR PRECISION MEDICINE (TOPMED) PROGRAM PROJECT STUDIES. DR. BOERWINKLE AND THE UTHEALTH GROUP WILL: €¢ WORK COLLABORATIVELY WITH DR. GIBBS AND THE BCM HGSC ON DATA INTEGRATION, DATA FORMATS, QUALITY CONTROL AND QUALITY ASSURANCE, AND OTHER ISSUES DESIGNATED BY NHLBI. €¢ WORK COLLABORATIVELY WITH METABOLON AND THE BCM HGSC TO GENERATE A MANUAL OF OPERATIONS (MOO) PROVIDING DETAILED STANDARD OPERATING PROCEDURES FOR ALL STEPS IN THE WORKFLOW. €¢ OVERSEE THE GENERATION OF METABOLITE PROFILE DATA BY METABOLON, INC., ENSURING THAT ALL WORK PRODUCT CONFORMS TO THE SPECIFICATIONS IN THE CONTRACT STATEMENT OF WORK (SEE ATTACHMENT 2A NOTICE OF AWARD WITHIN THIS AGREEMENT), INCLUDING, BUT NOT LIMITED TO, METHODS AND PROTOCOLS, DATA QUALITY, AND DATA CLASSIFICATION. €¢ OVERSEE THE SECURE TRANSMISSION OF PROJECT DATA TO THE PROJECT STUDIES, THE TOPMED DATA COORDINATING CENTER (DCC) AND/OR THE TOPMED INFORMATICS RESEARCH CENTER (IRC). €¢ CONTRIBUTE TO CONTRACT REPORTING REQUIREMENTS AND OTHER AD HOC REQUESTS FROM THE TOPMED PROGRAM. €¢ PROVIDE BCM HGSC NECESSARY INFORMATION FOR PROJECT INVOICING, IN A FORMAT TO BE COLLABORATIVELY DETERMINED BY BCM HGSC AND UTHEALTH.

OF MULTI-OMICS DATA AND DATA PROCESSING PIPELINES IN COLLABORATION WITH DR. ALBERT SMITH. DR. BING YU WILL PARTICIPATE AND OVERSEE METABOLOMICS DATA PROCESSING AND GENERATION OF METABOLITE QTLS WITH DR. CHEN. DR. FORNAGE WILL DEVELOP AND VALIDATE A METHYLATION QC PIPELINE. DRS. SARNOSKI AND JUN WILL OVERSEE THE PROTEOMICS DATA PROCESSING AND GENERATION OF PQTLS. MS. GROVE WILL COORDINATE THE MULTI-OMICS DATA PROGRAM, OVERSEE DATA DISTRIBUTION AND MANAGEMENT, AND PARTICIPATE IN THE DEVELOPMENT OF DATA PROCESSING PIPELINES FOR METHYLATION AND METABOLOMICS AS NEEDED. ALL INVESTIGATORS WILL PARTICIPATE IN PRESENTATION OF RESULTS AND DEVELOPMENT OF MANUSCRIPTS.