Regents Of The University Of California, SAN Francisco, The

SUBPOPULATIONS AND INTERMEDIATE OUTCOMES IN COPD (SPIROMICS) III - TASK AREA A - YEAR 3

MULTI-SPECIALTY RADIOLOGY PHYSICIAN SERVICES

ESTABLISH A STUDY ON THE IMPACT OF SLAUGHTER LINE SPEED ON WORKER SAFETY IN BOTH YOUNG CHICKEN AND SWINE SLAUGHTER ESTABLISHMENTS.

SCOPE OF WORK STATEMENT THE SCOPE OF WORK STATEMENT MUST INCLUDE THE PROJECT TITLE, START/END DATES, PI NAME, AND PROJECT DESCRIPTION (INCLUDING OBJECTIVES, TASKS, AND DELIVERABLES). WHILE EXACT EXPERIMENTAL OR PROCEDURAL INFORMATION IS NOT NECESSARY, THE SCOPE OF WORK STATEMENT SHOULD PROVIDE SUFFICIENT DETAIL ABOUT THE PROPOSED WORK TO ALLOW SOMEONE REVIEWING THE STATEMENT AND WHO WAS FAMILIAR WITH THE PROJECT TO DETERMINE WHETHER OR NOT THE WORK AGREED TO WAS ACTUALLY PERFORMED PROJECT TITLE: TUBERCULOSIS EPIDEMIOLOGIC STUDIES CONSORTIUM III (TBESCIII) ESTIMATED DATES: 9/29/2021 TO 3/28/2026 SUBCONTRACTOR PI NAME: AMY SHEN TANG, MD, DIRECTOR OF IMMIGRANT HEALTH, NORTH EAST MEDICAL SERVICES PROJECT DESCRIPTION (INCLUDING OBJECTIVES, TASKS, AND DELIVERABLES AS APPLICABLE): OBJECTIVE: IDENTIFY INTERVENTIONS THAT ARE COST-EFFECTIVE IN INCREASING TB TESTING AND LTBI TREATMENT AND COMPLETION AMONG FOREIGN-BORN PERSONS SEEKING PRIMARY CARE IN A COMMUNITY HEALTH SETTING TASKS: IF AWARDED TBESCIII FUNDS, NORTH EAST MEDICAL SERVICES (NEMS) WILL EXECUTE A MEMORANDUM OF UNDERSTANDING AND/OR DATA USE AGREEMENT WITH UCSF AT THE START OF THE PROJECT PERIOD. NEMS WITH THEN WORK WITH DR. PRIYA SHETE€„¢S TEAM AT UCSF TO DESIGN A STUDY PROTOCOL FOR IMPLEMENTATION OF NEW OR ENHANCED SYSTEMS-, PROVIDER-, AND PATIENT-LEVEL INTERVENTIONS THAT PROMOTE TB SCREENING, TESTING AND LTBI TREATMENT AT NEMS€„¢ VARIOUS CLINIC SITES. NEMS WILL INVOLVE KEY PERSONNEL IN IT, INFORMATICS, AND ELECTRONIC HEALTH RECORDS (EHR) DEPARTMENTS TO HELP WITH DATA EXTRACTION AND MAKE EHR MODIFICATIONS THAT WILL IMPROVE AND OPTIMIZE LTBI CARE CASCADE WORKFLOWS. NEMS WILL RECRUIT ADMINISTRATIVE PERSONNEL TO ENSURE COMPLIANCE WITH STUDY PROTOCOLS AND SMOOTH IMPLEMENTATION OF MULTIPHASE STUDY INTERVENTIONS AT VARIOUS SITES. NEMS WILL ALSO RECRUIT KEY CLINICAL STAFF INCLUDING PHARMACISTS AND MID-LEVEL PRACTITIONERS FOR IMPLEMENTING CLINICAL INTERVENTIONS, AND PATIENT OUTREACH COORDINATORS/COMMUNITY HEALTH WORKERS WHO WILL CONDUCT CULTURALLY SENSITIVE TB OUTREACH AND EDUCATION AND OTHER SERVICES ADDRESSING SOCIAL DETERMINANTS OF HEALTH. DELIVERABLES: 1. EXECUTE MOU (WITHIN 2 MONTHS OF AWARD) AND DUAS AS NEEDED 2. IMPLEMENT AGREED UPON STUDY PROTOCOLS/INTERVENTIONS ACCORDING TO STUDY TIMELINE 3. SUBMIT BASELINE AND QUARTERLY EHR DATA REPORTS TO UCSF FOR ANALYSIS

THIS DATA COLLECTION STUDY IS BEING CONDUCTED TO ADVANCE THE DEVELOPMENT OF POCUS TECHNOLOGY BY DEVELOPING AI TOOLS TO AID IN THE DETECTION OF ICP CHANGES IN PATIENTS WITH ACQUIRED BRAIN INJURY. THIS PROTOCOL EVALUATES THE ENHANCED CAPABILITY OF AUTOMATED 4D ULTRASOUND SYSTEMS CONSISTING OF A PROTOTYPE E4D ULTRASOUND PROBE, ULTRASOUND SYSTEM CAPABLE 2-D BI-PLANE AND 4-D OPHTHALMIC IMAGING MODES, AND AI TOOLS TO AUTOMATICALLY MEASURE ONSD TO BE USED TO MONITOR OCULAR AND ICP CHANGES.

UCSF WILL PROVIDE THE SCIENTIFIC LEAD. WILL PROVIDE SCIENTIFIC STAFF W/ KNOWLEDGE IN DATA SCIENCES, CLINICAL AND HEALTH DATA, IMMUNOLOGY AND BIOINFORMATICS AS NEEDED.

THE PAIN TRIAL IS A 4 YEAR (3-YEAR ENROLLMENT) MULTICENTER, PREHOSPITAL, RANDOMIZED, DOUBLE-BLIND, CLINICAL TRIAL COMPARING FENTANYL VERSUS SUB-DISSOCIATIVE KETAMINE FOR MORTALITY OUTCOME DIFFERENCES, SAFETY, AND ANALGESIA IN TRAUMA PATIENTS WITH COMPENSATED SHOCK.